29th jsbms program1

The 29th Annual Meeting of the Japanese Society

for Biomedical Mass Spectrometry

Program

September 10

September 9 (Thu.)

8:55～9:00

Opening Remark

9:00～10:00

Oral Presentation (G1-G4)

G1	Retrospective study of patients with methylmalonic acidemia by ESI-MS/MS analysis
	Hironori KOBAYASHI, Yuki HASEGAWA, Masahiko KIMURA, Yuka YOTSUMOTO,
	Seiji YAMAGUCHI
	Department of Pediatrics, Shimane University School of Medicine

G2	Gas chromatography-mass spectrometric measurement of 3-hydroxyglutaric acid and
	related metabolites in patients with glutaric aciduria type I found in newborn screening
	using tandem mass spectrometry.
	Yosuke SHIGEMATSU¹, Ikue HATA², Go TAJIMA³, Nobuo SAKURA³, Toru YORIFUJI⁴
	1. Department of Health Science, School of Nursing, University of Fukui
	2. Department of Pediatrics, University of Fukui
	3. Department of Pediatrics, Hiroshima University
	4. Department of Pediatrics, kyoto University

G3	Gas chromatographic-mass spectrometric diagnosis of tyrosinemia type I using filter paper
	absorbed urine
	^{Toshihiro SHINKA, Tomiko KUHARA}
	Division of Human Genetics, Medical Research Institute, Kanazawa Medical University

G4	Chemical Diagnosis for Primary Hyperoxaluria Type II
	Analysis of Optical Isomer of Glyceric Acid by GC/MS as Diastereoisomeric
	Derivatives－
	Yoshito INOUE, Toshihiro SHINKA, Morimasa OHSE, Tomiko KUHARA
	Division of Human Genetics, Medical Research Institute, Kanazawa Medical University

10:00～11:00

Oral Presentation Ⅱ (G5－G8)

G5	Studies on brain uptake of neurotoxic metabolites derived from butyrophenones by brain microdialysis.
	Yuki MURABAYASHI¹, Youji KITAMURA¹, Fumiyo KASUYA^1, ², Kazuo IGARASHI^1, ²
	1. Faculty of Pharmaceuteical Sciences, Kobegakuin University
	2. High technology Research Center, Kobegakuin University

G6	Simple analysis of triazolam in human body fluids by HPLC-MS/MS
	Xiao-Pen LEE¹, Takeshi KUMAZAWA¹, Tetsuya ARINOBU², Hideki HATTORI³, Hiroshi SENO³, Keizo SATO¹
	1. Department of Legal Medicine, Showa University School of Medicine
	2. Department of Chemistry, Aichi Medical University School of Medicine
	3. Department of Legal Medicine, Aichi Medical University School of Medicine

G7	Examination of the simultaneous endocannabinoids assay in medical samples by LCMS/MS system
	Toru OBATA¹, Mayumi NOMURA¹, Youichi KASE², Yasumasa TANIFUJI²
	1. Department of Molecular Cell Biology, Institute of DNA Medicine, Jikei University School of Medicine
	2. Department of Anesthesiology, Jikei University School of Medicine

G8	High-throughput quantitative analysis by laser desorption: Measurement of serum salicylate levels by DIOS-MS
	Yoshinao WADA^1,2, Shoji OKUNO²
	1. Department of Molecular Medicine, Osaka MCHRI
	2. Japan Science & Technology Agency, Innovation Plaza Osaka

11:00～12:00

Workshop I "New Technologies in Biomedical Mass Spectrometory

W1-1	New MS Technologies for Medical/Clinical Applications Waters Offers
	Michiko KANAI, Kiyoshi MARUNO and Katsutoshi NAGASE
	Nihon Waters K.K.

W1-2	The Analysis Time Reduction using Fast-GC/MS and Database (organic and fatty acids)
	Katsuhiro NAKAGAWA, Shuichi KAWANA
	SHIMADZU CORPORATION

W1-3	Clinical Proteomics using SELDI-TOF MS
	Kenji SAITO
	Ciphergen Biosystems K.K.

W1-4	The advantage of high resolution and high mass accuracy measurement in proteomics study produced by
	the Finnigan LTQ FT linear ion trap/ICR hybrid mass spectrometer
	Masayuki KUBOTA
	Technical Lab, Thermo Electron Corporation, Yokohama, JAPAN

12:00～13:00

Lunch Time (Board Meeting)

13:00～13:30

Meeting of JSBMS Members

13:30～13:50

Award Lecture

	Application of delayed extraction matrix-assisted laser desorption ionization
	time-of-flightmass spectrometry for analysis of sphingolipids
	in patients with sphingolipidosis
	Takehisa FUJIWAKI
	Department of Pediatrics, Shimane University School of Medicine

13:50～14:10

Educational Lecture I

	Rapid analysis of volatile hydrocarbons in whole blood using solid-phase
	microextraction with gas chromatography-mass spectrometry, and its application in
	forensic cases to evaluate whether or not victims inhaled combustion gases and
	determine the gases inhaled
	Masanori HASEGAWA¹1, Yoko HIEDA², Haruo TAKESHITA², Kojiro KIMURA³
	1. Criminal Investigation Laboratory, Shimane Prefectural Police Headquarters
	2. Department of Legal Medicine, Shimane University School of Medicine
	3. Department of Legal Medicine, Graduate School of Biomedical Sciences, Hiroshima University

14:10～15:25

Oral Presentation Ⅲ (G9－G13)

G9	Determination of methamphetamine and amphetamine by stir bar sorptive extraction
	(SBSE)-gas chromatography/mass spectrometry
	Takeshi KUMAZAWA¹, Kenji HARA², Xiao-Pen LEE¹, Tetsuya ARINOBU³, Hideki
	HATTORI⁴, Hiroshi, SENO⁴, Akira ISHII⁵, Osamu SUZUKI⁶, Keizo SATO¹
	1. Department of Legal Medicine, Showa University School of Medicine
	2. Department of Forensic Medicine, Fukuoka University School of Medicine
	3. Department of Chemistry, Aichi Medical University School of Medicine
	4. Department of Legal Medicine, Aichi Medical University School of Medicine
	5. Department of Legal Medicine, Fujita Health University School of Medicine
	6. Department of Legal Medicine, Hamamatsu University School of Medicine

G10	Skin analysis of hydrocarbons for the diagnosis of dermal exposure to petroleum
	products in forensic and clinical cases
	Yoko HIEDA¹, Yoshio TSUJINO², Haruo TAKESHITA¹
	1. Department of Legal Medicine, Shimane University School of Medicine
	2. Department of Dermatology, Shimane University School of Medicine

G11	Development of GC-MS Identification System for Benzodiazepines and Their Metabolites
	H. NISHIOKA, M. NISHIKAWA, and H. TSUCHIHASHI
	Forensic Science Laboratory, Osaka Prefectural Police Headquarters

G12	Development and clinical meaning of analysis of SUPERUMIN in urine
	by GC/MS
	Hitoshi TANAKA1, Kenji HARA², Masayuki KASHIWAGI², Mituyoshi
	KAGEURA², Seiichi KASHIMURA², Keiichi TANAKA¹
	1.Departments of Emergency and Critical Care Medicine, Forensic Fukuoka University School of Medicine
	2, Departments of Emergency and Forensic Medicine, Fukuoka University School of Medicine

G13	Simultaneous determination of alpha-methyltryptamine and
	5-methoxy-N,N-diisopropyltryptamine in human blood and urine by GC/MS
	Tomomi ISHIDA, Keiko KUDO, Noriaki IKEDA
	Department of Forensic Pathology and Sciences, Graduate School of Medical
	Sciences, Kyushu University

15:25～15:45

Coffee Break

15:45～17:15

Oral Presentation Ⅳ (G14－G19)

G14	MALDI-TOFMS analysis of apoptosis related-proteins in mouse hepatocyte stimulated by glycyrrhizin
	Shigeo IKEGAWA
	Department of Bioanalytical Pharmaceutics, Faculty of Pharmaceutical Sciences, Kinki University

G15	Proteomics to identify antibodies against lung adenocarcinoma-derived
	proteins
	Toyofumi NAKANISHI¹, Hitoshi MURAO², Toru TAKEUCHI¹, Isao GOTO³, Hiroyuki SUZUKI⁴, Ikuya YANO⁴,
	Akira SHIMIZU¹^,²
	1Department of Clinical Pathology
	2Central Laboratory
	３First Internal　Medicine, Osaka Medical College,
	4Japan BCG Laboratory

G16	Technical developments for improving peptide mass fingerprinting: Use of a thin-layer gel and its preparation
	Yoshinao WADA^1,2, Michiko TAJIRI²
	1. Department of Molecular Medicine, Osaka MCHRI
	2. Japan Science & Technology Agency, Innovation Plaza Osaka

G17	A stable-isotopic study of placental transfer of maternal cholesterol –part I–
	Shuumi YOSHIDA¹, Yoshinao WADA^1,2
	1. Osaka University, Graduate School of Medicine
	2. Department of Molecular Medicine, Osaka MCHRI

G18	LC/ESI-MS analysis of phospholipid oxidation products in rat
	Junko ADACHI, Naoki YOSHIOKA, Yoshimi SAEKI, Mariko SATO, Rika FUNAE,
	Yasuhiro UENO
	Dept of Legal Medicine, Kobe University Graduate School of Medicine

G19	Effect of mutated TAP2 (TAP2*Bky2) on MHC Class I presenting peptides
	Gouichi KAGEYAMA¹, Seiji KAWANO¹, Sugayo KANAGAWA¹, Toyofumi NAKANISHI², Akira SHIMIZU²,
	Masahiro KOSHIBA¹, Shunichi KUMAGAI¹
	1. Clinical Pathology and Immunology, Department of Biomedical Informatics,
	Kobe University Graduate School of Medicine
	2. Department of Clinical Pathology, Osaka Medical College

17:15～18:15

Special Lecture

	A prospect of metabolomics - focused on lipidomics -
	Ryo TAGUCHI
	Department of Metabolome Graduate School of Medicine, The
	University of Tokyo

18:30～20:30

Banquet