PrognosisBone damage tends to become refractory in some cases, but to remit by treatment such as vitamin D2 or activated Vitamin D3 treatment as a whole.
However, renal damage progresses to advanced renal failure(Fig.8), and some cases of uremia need hemodialysis. Anemia also develops in proportion to the degree of renal failure.
Survival rate of itai-itai disease patients is significantly lower than that of controls (Fig.9), and especially life prognosis of cases with severe renal damage is unfavorable.
| Fig.8@ | Progression of renal damage of itai-itai disease patients. Increase of serum creatinine shows development of renal failure. |
| Fig.9@ | Survival rates of itai-itai disease patients and subjects suspected of having the disease are significantly lower as compared with controls. |
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