著書・総説など

原著論文（2017年以降）

2018年

小内伸幸，川村俊輔，樗木俊聡

単球由来マクロファージの前駆細胞

炎症と免疫 26(3): 17(201)-24(208), 2018

2017年

小内伸幸

樹状細胞分化の制御機構

臨床免疫・アレルギー科 67(6): 545-552, 2017

小内伸幸

単核貪食細胞（樹状細胞/単球/マクロファージ）の起源・発生・分化制御

金沢医科大学雑誌 42(3): 69-74, 2017

小内伸幸

Blastic plasmacytoid dendritic cell neoplasmの前駆細胞である形質細胞様樹状細胞とは

血液内科  74(6): 759-764, 2017

小内伸幸

単核貪食細胞（単球/マクロファージ/樹状細胞）の起源・発生・細胞分化

感染 炎症 免疫  47 (1): 72-75, 2017

小内伸幸

血球貪食症候群の発症機構と免疫学意義

血液内科 75(5): 591-597, 2017

2021年

Onai N*, Ogasawara C

Calcium Pyrophosphate Dihydrate Crystals Increase the Granulocyte/Monocyte Progenitor (GMP) and Enhance Granulocyte and Monocyte Differentiation In Vivo.

Int J Mol Sci, 22:262. https://doi.org/10.3390/ijms22010262, (2021)

2020年

Yabe-Wada T*, Philpott CC, Onai N*

PCBP2 post-transcriptionally regulates sortilin expression by binding to a C-rich element in its 3' UTR.

FEBS Open Bio, 10:407-413, https://doi.org/10.1002/2211-5463.12794 (2020)

2018年

Yabe-Wada T*, Matsuba S, Unno M, Onai N*

Crystal structure of the ligand‐free form of the Vps10 ectodomain of dimerized Sortilin at acidic pH

FEBS Lett, 592: 2647-2657, (2018) LINK, PDB; 5ZNN

2017年

Matsuba S, Yabe-Wada T, Takeda K, Sato T, Suyama M, Takai T, Kikuchi T, Nukiwa T, Nakamura A

Identification of SLPI as an endogenous negative regulator in allergic effector cells

Front Immunol, 8:1538. doi:10.3389/fimmu.2017.01538, (2017) LINK

Onai N, Asano J, Kurosaki R, Kuroda S, Ohteki T.

Flexible fate commitment of E2-2high common DC progenitors implies tuning in tissue microenvironments.

Int Immunol, 29: 443-456 (2017) LINK

Matsuda K, Okamoto N, Kondo M, Arkwright PD, Karasawa K, Ishizaka S, Yokota S, Matsuda A, Jung K, Oida K, Amagai Y, Jang H, Noda E, Kakinuma R, Yasui K, Kaku U, Mori Y, Onai N, Ohteki T, Tanaka A, Matsuda H.

Mast cell hyperactivity underpins the development of oxygen-induced retinopathy.

J Clin Invest, 127(11):3987-4000, (2017)  LINK

Asano J, Sato T, Ichinose S, Kajita M, Onai N, Shimizu S, Ohteki T

Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration.

Cell Rep, 20(5):1050-1060, (2017) LINK

Kawamura S, Onai N, Miya F, Sato T, Tsunoda T, Kurabayashi K, Yotsumoto S, Kuroda S, Takenaka K, Akashi K, Ohteki T

Identification of a Human Clonogenic Progenitor with Strict Monocyte Differentiation Potential: A Counterpart of Mouse cMoPs

Immunity, 46: 835-848, (2017) LINK

原著論文

Yabe-Wada T*, Matsuba S, Takeda K, Sato T, Suyama M, Ohkawa Y, Takai T, Shi H, Philpott CC, Nakamura A

TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin

Sci Rep, 6, 26566; doi: 10.1038/srep26566  (2016) LINK

Ohyagi H#, Onai N#, Sato T, Yotsumoto Y, Liu J, Akiba H, Yagita H, Atarashi K, Honda K, Roers A, Müller W, Kurabayashi K, Hosoi-Amaike M, Takahashi N, Hirokawa M, Matsushima K, Sawada K, Ohteki T

Monocyte-derived dendritic cells perform hemophagocytosis to fine-tune excessive immune responses.

Immunity, 39: 584-598 (2013) (#These authors contributed equally to this work) LINK

Onai N, Kurabayashi K, Hosoi-Amaike M, Toyama-Sorimachi N, Matsushima K, Inaba K, Ohteki T.

A clonogenic progenitor with prominent plasmacytoid dendritic cell developmental potential.

Immunity,42: 943-957 (2013) LINK

Onai N, Obata-Onai A, Schmid MA, Ohteki T, Jarrossay D, Manz MG

Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow.

Nat Immunol, 8: 1207-1216 (2007) LINK

総説

Guilliams M*, Ginhoux F*, Jakubzick C*, Naik SH*, Onai N*, Schraml BU*, Segura E.*Tussiwand R*, Yona, S*

Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny.

Nat. Rev. Immunol. 14: 571-578 (2014) LINK

2016年以前の主な論文