医学部 臨床医学
一般・消化器外科学General and Digestive Surgery
研究室概要
【主な研究内容】
1.スフィンゴ脂質が大腸がんの発がん，進展，転移に及ぼす影響に関する研究
2.スフィンゴ脂質が NAFLD や肝発がんに及ぼす影響に関する研究
3.大腸がんや悪性軟部腫瘍における NANOG, ZFP57, Imprinting gene の機能解析．
4.蛍光標識による胃がんセンチネルリンパ節生検に基づく機能温存手術の妥当性に関する研究
5.消化器がんに対する腸管免疫強化療法の有用性に関する研究
6.進行胃がんに対する術前化学療法に関する研究
7.進行食道がん，進行直腸がん，進行膵がんに対する術前放射線化学療法に関する研究
8.進行大腸がんに対する術後補助化学療法に関する研究
9.敗血症の凝固・線溶異常に関する研究
10.肝移植を含めた肝臓外科手術における腸管免疫強化と抗血小板の有用性に関する研究
【主な診療分野】
上部消化管外科治療，下部消化管外科治療，肝胆膵脾外科治療，腹部ヘルニアの外科治療，腹部悪性軟部腫瘍の外科治療，肥満症の外科治療
【診療の基本方針】
1.低侵襲 minimally invasive
2.個別化 personalized
3.探索的 exploratory
4.経済的 cost-conscious
【教育・研修の基本方針】
1.技能 competence
2.意思伝達 communication
3.効率 cost performance"
お問い合わせ
TEL: 076-286-2211
/ FAX: 076-286-4626
e-mail: gastsurg@kanazawa-med.ac.jp
e-mail: gastsurg@kanazawa-med.ac.jp
所属者紹介
主な研究業績
- Miyata T, Shinden Y, Motoyama S, et al. Non-Alcoholic Fatty Liver Disease May Be a Risk Factor for Liver Metastasis After Radical Surgery for Colorectal Cancer: A Retrospective Study. J Gastrointest Cancer. 2024 Mar 19. doi: 10.1007/s12029-024-01042-6.
- Nakamura N, Kinami S, Kaida D, et al. Prognostic factors in T4b gastric cancer after surgery: A more balanced and sequential therapy for patients? J Cancer Res Ther. 20(1): 211-215, 2024.
- Kinami S, Kaida D, Okamoto K, et al. Long‑term survival prognosis of function‑preserving curative gastrectomy for early gastric cancer. Oncol Lett. 2024 Jan 22;27(3):115. doi: 10.3892/ol.2024.14248.
- Okamoto K, Inaki N, Saito H, et al. Analysis of factors associated with operative difficulty in thoracoscopic esophageal cancer surgery in the left-decubitus position: a single-center retrospective study. BMC Surg. 2023 Aug 18;23(1):242. doi: 10.1186/s12893-023-02131-2.
- Kin R, Hoshi D, Fujita H, et al. Prognostic significance of p16, p21, and Ki67 expression at the invasive front of colorectal cancers. Pathol Int. 73(2): 81-90, 2023.
主な外部研究資金
- TAKAMURA H. Grant-in-Aid for Scientific Research of the Ministry of Education, Science and Culture 2022; Basic research for the application of selective sphingomyelin synthase 2 inhibitor to the liver surgery.
- MIYATA T. Grant-in-Aid for Scientific Research of the Ministry of Education, Science and Culture 2021; Research for new biomarkers of the sinusoid obstructive syndrome of liver focusing on platelet aggregation.
- TOMITA Y. Grant-in-Aid for Scientific Research of the Ministry of Education, Science and Culture 2021; Suppression of colorectal cancer liver metastasis by inhibition of sphingomyelin synthase in fatty liver.
- NAKAMURA N. Grant-in-Aid for Scientific Research of the Ministry of Education, Science and Culture 2021; Research for the effects of sphingolipids on non-alcoholic fatty liver disease-related liver carcinogenesis.
- OKAMOTO K. Grant-in-Aid for Scientific Research of the Ministry of Education, Science and Culture 2018; Fundamental studies on tumor regulation through cellular senescence of fibroblasts in the cancer microenvironment.