英文論文

79) Tanida M, Hayata A, Shintani N, Yamamoto N, Kurata Y, Shibamoto T, Morgan DA, Rahmouni K, Hashimoto H. Central PACAP mediates the sympathetic effects of leptin in a tissue-specific manner. Neuroscience 2013 (in press).

78) Tanida M, Yamamoto N, Shibamoto T, Rahmouni K.. Involvement of Hypothalamic AMP-Activated Protein Kinase in Leptin-Induced Sympathetic Nerve Activation. PLoS One 8(2): e56660, 2013.

77) Shinomiya S, Shibamoto T, Kurata Y, Kuda Y, Zhang W, Tanida M, Toga H. Nitric oxide and β(2)-adrenoceptor activation attenuate pulmonary vasoconstriction during anaphylactic hypotension in anesthetized BALB/c mice. Exp Lung Res 2013 (in press)

76) Kitadate M, Shibamoto T, Tsutsumi M, Tonami H. Portal venular constriction during anaphylactic shock in anesthetized rats. Biomed Res 2013 (in press).

75) Suzuki S, Kurata Y, Li P, Notsu T, Hasegawa A, Ikeda N, Kato M, Miake J, Sakata S, Shiota G, Yoshida A, Ninomiya H, Higaki K, Yamamoto K, Shirayoshi Y, Hisatome I. Stabilization of Kv1.5 channel protein by bepridil through its action as a chemical chaperone. Eur J Pharmacol 696(1-3): 28-34, 2012.

74) Fujii H, Ikeuchi Y, Kurata Y, Ikeda N, Bahrudin U, Li P, Nakayama Y, Endo R, Hasegawa A, Morikawa K, Miake J, Yoshida A, Hidaka K, Morisaki T, Ninomiya H, Shirayoshi Y, Yamamoto K, Hisatome I. Electrophysiological properties of prion-positive cardiac progenitors derived from murine embryonic stem cells. Circ J 76(12): 2875-2883, 2012.

73) Zhang W, Shibamoto T, Kuda Y, Kurata Y, Shinomiya S, Kida M, Tsuchida H. Vascular perfusion limits mesenteric lymph flow during anaphylactic hypotension in rats. Am J Physiol Regul Integr Comp Physiol 302(10) R1191-R1196, 2012..

72) Kurata Y, Hisatome I, Shibamoto T. Roles of sarcoplasmic reticulum Ca cycling and Na/Ca exchanger in sinoatrial node pacemaking: insights from bifurcation analysis of mathematical models.Am J Physiol Heart Circ Physiol 302(11): H2285-H2300, 2012.

71) Zhang W, Shibamoto T, Kuda Y, Shinomiya S, Kurata Y. The responses of the hepatic and.splanchnic vascular beds to vasopressin in rats. Biomed Res 33(2): 83-88, 2012.

70) Shibamoto T, Tsutsumi M, Kuda Y, Ohmukai C, Zhang W, Kurata Y.：Mast cells are not involved in the ischemia-reperfusion injury in perfused rat liver. J Surg Res 174(1): 114-119, 2012

69) Urashima T, Kurata Y, Miake J, Kato M, Ogura K, Yano A, Adachi M, Tanaka Y, Yamada K, Hamada T, Mizuta E, Kuwabara M, Kato M, Yamamoto Y, Ogino K, Yoshida A, Shirayoshi Y, Hisatome I. Enhancing effects of salicylate on quinidine-induced block of human wild type and LQT3 related mutant cardiac Na+ channels. Biomed Res 32(5): 303-312, 2011.

68) Bahrudin U, Morikawa K, Takeuchi A, Kurata Y, et al:. Impairment of ubiquitin-proteasome system by E334K cMyBPC modifies channel proteins, leading to electrophysiological dysfunction.J Mol Biol 413(4): 857-878, 2011.

67) Ting Y, Morikawa K, Kurata Y, et al: Transcriptional activation of the anchoring protein. SAP97 by heat shock factor (HSF)-1 stabilizes K(v) 1.5 channels in HL-1 cells. Higaki K, Nanba E, Ninomiya H, Shirayoshi Y, Hisatome I. Br J Pharmacol 168(8): 1832-1842, 2011.

66) Li P, Ninomiya H, Kurata Y et al.：Reciprocal control of hERG stability by Hsp70 and Hsc70with implication for restoration of LQT2 mutant stability. Circ Res 108: 458-468, 2011.

65) Zhang W, Shibamoto T, Kuda Y, Ohmukai C, Kurata Y.：Pulmonary vasoconstrictive and bronchoconstrictive responses to anaphylaxis are weakened via beta₂-adrenoceptor activation by endogenous epinephrine in anesthetized rats. Anesthesiology 114: 614-623, 2011.

64) Kamikado C, Shibamoto T, Zhang W, Kuda Y, Ohmukai C, Kurata Y ：Portacaval shunting attenuates portal hypertension and systemic hypotension in rat anaphylactic shock.. J Physiol Sci 61(2):161-166, 2011.

63) Shibamoto T, Tsutsumi M, Ohmukai C, Kuda Y, Zhang W, Kurata Y：Ethanol predominantly constricts presinusoids of isolated perfused livers of rat, guinea pig, and mouse. Alcohol Alcohol 46(2): 117-122, 2011.

62) Zhang W, Shibamoto T, Kurata Y, Kohno H.：Effects of beta-adrenergic antagonists on anaphylactic hypotension in conscious rats. Eur J Pharmacol. 650:303-308, 2011.

61) Cui S, Shibamoto T, Zhang W, Kurata Y, Kashimura O, Miyamae S： Exercise training attenuates anaphylactic venoconstriction in rat perfused liver, but does not affect anaphylactic hypotension in conscious rats. Clin Exp Pharmacol Physiol. 37:889-893, 2010.

60) Takano H, Shibamoto T, Zhang W, Kurata Y： Liver volume, as assessed by four ultrasonic crystals arranged to form a tetrahedron, decreases during anaphylactic shock in anesthetized rats. Shock. 34:586-591, 2010

59) Morikawa K, Bahrudin U, Miake J, Igawa O, Kurata Y, Nakayama Y, Shirayoshi Y, Hisatome I：Identification, isolation and characterization of HCN4-positive pacemaking cells derived from murine embryonic stem cells during cardiac differentiation.Pacing Clin Electrophysiol., 33:290-303, 2010.

58) Kurata Y, Matsuda H, Hisatome I, Shibamoto T：Roles of hyperpolarization- activated current If in sinoatrial node pacemaking: insights from bifurcation analysis of mathematical models. Am J Physiol Heart Circ Physiol., 298:H1748-H1760, 2010.

57) Zhang W, Shibamoto T, Cui S, Takano H, Kurata Y.：7-nitroindazole, but not L-NAME or aminoguanidine, attenuates anaphylactic hypotension in conscious rats. Shock., 31:201-206, 2009.

56) Koshida S, Kurata Y, Notsu T, Hirota Y, Kuang TY, Li P, Bahrudin U, Harada S, Miake J, Yamamoto Y, Hoshikawa Y, Igawa O, Higaki K, Soma M, Yoshida A, Ninomiya H, Shiota G, Shirayoshi Y, Hisatome I：Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells.　Eur J Pharmacol., 604:93-102, 2009.

55) Zhao ZS, Shibamoto T, Tsutsumi M, Cui S, Zhang WM, Takano H, Kurata Y：Mouse hepatic portal venoconstrictive response to vasoconstrictors is much weaker than that in rat. J Cardiovasc Pharmacol., 54:421-426, 2009.

54) Takano H, Shibamoto T, Zhang W, Kurata Y, Toga H：Hepatic microvascular pressure during anaphylactic shock in anesthetized rats. Microvasc Res., 78:169-73, 2009.

53) Cui S, Shibamoto T, Zhang W, Takano H, Kurata Y：Venous resistance increases during rat anaphylactic shock., Shock, 29:733-739，2008.

52) Hirota Y, Kurata Y, Kato M, Notsu T, Koshida S, Inoue T, Kawata Y, Miake J, Bahrudin U, Li P, Hoshikawa Y, Yamamoto Y, Igawa O, Shirayoshi Y, Nakai A, Ninomiya H, Higaki K, Hiraoka M, Hisatome I：Functional stabilization of Kv1.5 protein by Hsp70 in mammalian cell lines., Biochem. Biophys. Res. Commun.，372:469-474，2008.

51) Kurata Y, Matsuda H, Hisatome I, Shibamoto T：Regional difference in dynamical property of sinoatrial node pacemaking: role of Na⁺ channel current., Biophys. J.，95:951-977，2008.

50) Shibamoto T, Kamikado C, Koyama S：Increased sinusoidal resistance is responsible for the basal state and endothelin-induced venoconstriction in perfused cirrhotic rat liver., Pflugers Arch.，456:467-477，2008.

49) Shibamoto T, Liu W, Cui S, Zhang W, Takano H, Kurata Y：PAF, rather than histamine, participates in mouse anaphylactic hypotension., Pharmacology.，82:114-120，2008.

48) Yano S, Miake J, Mizuta E, Manabe K, Bahrudin U, Morikawa K, Arakawa K, Sasaki N, Igawa O, Shigemasa C, Yamamoto Y, Morisaki T, Hidaka K, Kurata Y, Yoshida A, Shiota G, Higaki K, Ninomiya H, Lee JK, Shirayoshi Y, Hisatome I：Changes of HCN gene expression and If currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation., Biomed. Res.，29:195-203，2008.

47) Cui S, Shibamoto T, Zhao Z, Takano H, Kurata Y：l-NAME augments PAF-induced venoconstriction in isolated perfused livers of rat and guinea pig, but not mouse，Prostaglandins Leukot. Essent. Fatty Acids.，76:277-283，2007.

46) Cui S, Shibamoto T, Zhao Z, Zhang W, Takano H, Kurata Y：Effects of L-NAME on thromboxane A₂-induced venoconstriction in isolated perfused livers from rat, guinea pig and mouse，Vascul. Pharmacol.，47:215-221，2007.

45) Cui S, Shibamoto T, Takano H, Zhang W, Kurata Y：Leukotrienes and cyclooxygenase products mediate anaphylactic venoconstriction in ovalbumin sensitized rat livers，Eur. J. Pharmacol.，576:99-106，2007.

44) Kurata Y, Matsuda H, Hisatome I, Shibamoto T：Effects of pacemaker currents on creation and modulation of human ventricular pacemaker: theoretical study with application to biological pacemaker engineering，Am. J. Physiol. Heart Circ. Physiol.，292:H701-718，2007.

43) Liu W, Takano H, Shibamoto T, Cui S, Zhao Z-S, Zhang W, Kurata Y：Involvement of splanchnic vascular bed in anaphylactic hypotension in anesthetized BALB/c mice，Am. J. Physiol. Regul. Integr. Comp. Physiol.，293:R1947-1953，2007.

42) Ogura K, Miake J, Sasaki N, Iwai C, Bahrudin U, Li P, Kato M, Iitsuka K, Hirota Y, Koshida T, Yamamoto Y, Inoue Y, Yano A, Adachi M, Igawa O, Kurata Y, Morisaki T, Shiota G, Shirayoshi Y, Ninomiya H, Hisatome I：Inhibition of β-adrenergic signaling by intracellular AMP is independent of cell-surface adenosine receptors in rat cardiac cells，J. Mol. Cell. Cardiol.，43:648-652，2007.

41) Shibamoto T, Shimo T, Cui S, Zhang W, Takano H, Kurata Y, Tsuchida H：The roles of mast cells and Kupffer cells in rat systemic anaphylaxis，Am. J. Physiol. Regul. Integr. Comp. Physiol.，293:R2202-R2209，2007.

40) Shibamoto T, Ruan Z, Cui S, Liu W, Zhao Z-S, Takano H, Kurata Y, Koizumi T, Kubo K：The sinusoidal pressure during ischemia-reperfusion injury in perfused mouse liver pretreated with or without L-NAME，J. Surg. Res.，139:30-35，2007.

39) Takano H, Lui W, Zhao Z, Cui S, Zhang W, Shibamoto T：NG-nitro-L-arginine methyl ester, but not methylene blue, attenuates anaphylactic hypotension in anesthetized mice，J. Pharmacol. Sci.，104::212-217，2007.

38) Watanabe K, Koizumi T, Ruan Z, Kubo K, Sakai A, Shibamoto T：Reduced pulmonary vascular reactivity after cold exposure to acute hypoxia: A role of nitric oxide (NO)，High Alt. Med. Biol.，8:43-49，2007.

37) Zhao Z, Shibamoto T, Cui S, Takano H, Zhang W, Kurata Y：Head-down tilt posture attenuates anaphylactic hypotension in mice and rats，J. Physiol. Sci.，57:269-274，2007.

36) Karasawa N, Shibamoto T, Cui S, Takano H, Kurata Y, Tsuchida H：Hepatic pre-sinusoidal vessels contract in anaphylactic hypotension in rabbits，Acta Physiol. Scand.，189：15-22，2007.

35) Sonoyama K, Ninomiya H, Igawa O, Kaetsu Y, Furuse Y, Hamada T, Miake J, Li P, Yamamoto Y, Ogino K, Yoshida A, Taniguchi S, Kurata Y, Matsuoka S, Narahashi T, Shiota G, Nozawa Y, Matsubara H, Horiuchi M, Shirayoshi Y, Hisatome I：Inhibition of inward rectifier K+ currents by angiotensin Ⅱ in rat atrial myocytes: Lack of effects in cells from spontaneous hypertensive rats，Hypertens. Res.，29: 923-934，2006.

34) Mizuta E, Furuichi H, Kazuki Y, Miake J, Yano S, Bahrudin U, Yamamoto Y, Igawa O, Shigemasa C, Hidaka K, Morisaki T, Kurata Y, Ninomiya H, Kitakaze M, Shirayoshi Y, Oshimura M, Hisatome I：Delayed onset of beating and decreased expression of T-type Ca²⁺channel in mouse ES cell-derived cardiocytes carrying human chromosome 21，Biochem. Biophys. Res. Commun.，351:126-132，2006.

33) Cui S., Shibamoto T, Liu W, Takano H, Kurata Y：Effects of platelet-activating factor, thromboxane A₂ and leukotriene D₄ on isolated perfused rat liver，Prostaglandins Other Lipid Mediat.，80:35-45，2006.

32) Cui S., Shibamoto T, Liu W, Takano H, Zhao Z-S, Kurata Y：Effects of Hct on L-NAME-induced potentiation of anaphylactic presinusoidal constriction in perfused rat livers，J. Cardiovasc. Pharmacol.，48:827-833，2006.

31) Cui S., Shibamoto T, Ruan Z, Takano H, Liu W, Kurata Y：Oxygen consumption, assessed with the oxygen absorption spectrophotometer, decreases independently of venoconstriction during hepatic anaphylaxis in perfused rat liver，Shock，26:62-68，2006.

30) Shibamoto T, Ishibashi T, Shimo T, Cui S, Takano H, Tsuchida H, Nishio M, Kurata Y：N^G-nitro-L-arginine methyl ester potentiates anaphylactic venoconstriction in rat perfused livers，Clin. Exp. Pharmacol. Physiol.，33:1073-1077，2006.

29) Sonoyama K,.Igawa O, Miake J, Yamamoto Y, Sugihara S, Sasaki N, Shimoyama M, Hamada T, Taniguchi S, Yoshida A, Ogino K, Shigemasa C, Hoshikawa Y, Kurata Y, Shiota G, Narahashi T, Horiuchi M, Matsubara H, Ninomiya H, Hisatome I：Effects of angiotensin II on the action potential durations of atrial myocytes in hypertensive rats，Hypertens. Res.，28: 173-179，2005.

28) Tanaka H, Miake J, Notsu T, Sonoyama K, Sasaki N, Iitsuka K, Kato M, Taniguchi S, Igawa O, Yoshida A, Shigemasa C, Hoshikawa Y, Kurata Y, Kuniyasu A, Nakayama H, Inagaki N, Nanba E, Shiota G, Morisaki T, Ninomiya H, Kitakaze M, Hisatome I：Proteasomal degradation of Kir6.2 channel protein and its inhibition by a Na⁺ channel blocker aprindine，Biochem Biophys Res Commun，331: 1001-1006，2005.

27) Shibamoto T, Ruan Z, Cui S, Kurata Y, Koizumi T, Kubo K：Anaphylactic hepatic venoconstriction is attenuated by nitric oxide released via shear stress-dependent and -independent mechanisms in guinea pig，Clin. Exp. Pharmacol. Physiol.，32:288-293，2005.

26) Shibamoto T, Cui S, Ruan Z, Kurata Y：Effects of norepinephrine and histamine on vascular resistance in isolated perfused mouse liver，Jpn. J. Physiol.，55:143-148，2005.

25) Ruan Z, Koizumi T, Sakai A, Ishizaki T, Kubo K, Shibamoto T, Wang Z：Comparison of cardiopulmonary response to endogenous nitric oxide inhibition in pigs inhabited at three levels of altitude，Eur. J. Appl. Physiol.，94:93-96，2005.

24) Shibamoto T, Cui S, Ruan Z, Liu W, Takano H, Kurata Y：Hepatic venoconstriction is involved in anaphylactic hypotension in rats，Am. J. Physiol. Heart Circ. Physiol.，289:H1436-H1444，2005.

23) Kato M, Ogura K, Miake J, Sasaki N, Taniguchi S, Igawa O, Yoshida A, Hoshikawa Y, Murata M, Nanba E, Kurata Y, Kawata Y, Ninomiya H, Morisaki T, Kitakaze M, Hisatome I：Evidence for proteasomal degradation of Kv1.5 channel protein，Biochem Biophys Res Commun.，337: 343-348，2005.

22) Hongo M, Mawatari E, Sakai A, Ruan Z, Koizumi T, Terasawa F, Yazaki Y, Kinoshita O, Ikeda U, Shibamoto T：Effects of nicorandil on monocrotaline-induced pulmonary arterial hypertension in rats，J. Cardiovasc. Pharmacol.，46:452-458，2005.

21) Kurata Y, Hisatome I, Matsuda H, Shibamoto T：Dynamical mechanisms of pacemaker generation in IK1-downregulated human ventricular myocytes: insights from bifurcation analyses of a mathematical model，Biophys. J.，89:2865-2887，2005.

20) Shibamoto T, Ruan Z, Cui S, Liu W, Kurata Y：Involvement of platelet-activating factor and leukotrienes in anaphylactic segmental venoconstriction in ovalbumin sensitized guinea pig livers，Prostaglandins Other Lipid Mediat.，78:218-230，2005.

19) Miyamae S：Stoichiometry of the sodium-calcium exchanger in cardiac muscle，J. Kanazawa. Med. Univ.，30:306-312，2005.

18) Takano H, Dora K.A, Garland C.J：Spreading vasodilatation in resistance arteries，J. Smooth Muscle Res.，41:303-311，2005.

17) Kamikado C, Shibamoto T, Hongo M, Koyama S.：Effects of Hct and norepinephrine on segmental vascular resistance distribution in isolated perfused rat livers，Am. J. Physiol. Heart Circ. Physiol.，286:H121-H130，2004.

16) Ruan Z, Shibamoto T, Shimo T, Tsuchida H, Koizumi T, Nishio M：NO, but not CO, attenuates anaphylaxis-induced postsinusoidal contraction and congestion in guinea pig liver，Am. J. Physiol. Regul. Integr. Comp. Physiol.，286:R94-R100，2004.

15) Shibamoto T, Narushima M, Ling YQ, Shimo T, Tsuchida H, Kurata Y, Ogura T.：Different hepatic vascular response to noradrenaline and histamine between guinea pig and rat，Acta Physiol. Scand.，180:255-263，2004.

14) Matsuda H, Kurata Y, Imanishi S, Sato R, Shibamoto T：Effects of Angiotensin II on sustained outward currents in rat ventricular myocytes，Pflugers Arch.，448:54-62，2004.

13) Ruan Z, Shibamoto T, Shimo T, Koizumi T, Tsuchida H, Kurata Y, Ogura T, Kubo K：Effects of platelet-activating factor and thromboxane A₂ on isolated perfused-guinea pig liver，Prostaglandins Other Lipid Mediat.，73:73-85，2004.

12) Miake J, Kurata Y, Iizuka K, Furuichi H, Manabe K, Sasaki N, Yamamoto Y, Hoshikawa Y, Taniguchi S, Yoshida A, Igawa O, Makita N, Shiota G, Nanba E, Ohgi S, Narahashi T, Hisatome I：State-dependent blocking actions of azimilide dihydrochloride (NE-10064) on human cardiac Na⁺ channels，Circ J.，68:703-711，2004.

11) Manabe K, Miake J, Sasaki N, Furuichi H, Yano S, Mizuta E, Yamamoto Y, Hoshikawa Y, Yamazaki H, Tajima F, Shiota G, Nanba E, Ohgi S, Hidaka K, Morisaki T, Kurata Y, Lee JK, Igawa O, Shigemasa C, Hisatome I.：Developmental changes of Ni²⁺ sensitivity and automaticity in Nkx2.5-positive cardiac precursor cells from murine embryonic stem cell，Circ J.，68:724-726，2004.

10) Ogura T, Matsuda H, Shibamoto T, Imanishi S：Osmosensitive properties of rapid and slow delayed rectifier K⁺ currents in guinea-pig heart cells，Clin. Exp. Pharmacol. Physiol.，30: 616-622，2003.

9) Kurata Y, Hisatome I, Imanishi S, Shibamoto T：Roles of L-type Ca²⁺ and delayed-rectifier K⁺ currents in sinoatrial node pacemaking:insights from stability and bifurcation analyses of a mathematical model，Am. J. Physiol. Heart Circ. Physiol.，285: H2804-H2819，2003.

8) Kaneki T, Koizumi T, Yamamoto H, Fujimoto K, Kubo K, Shibamoto T：Effects of resuscitation with hydroxyethyl starch (HES) on pulmonary hemodynamics and lung lymph balance in hemorrhagic sheep; comparative study of low and high molecular HES，Resuscitation，52: 101-108，2002.

7) Ogura T, Imanishi S, Shibamoto T：Osmometric and water-transporting properties of guinea pig cardiac myocytes，Jpn. J. Physiol.，52: 333-342，2002.

6) Ogura T, Matsuda H, Imanishi S, Shibamoto T：Sarcolemmal hydraulic conductivity of guinea-pig and rat ventricular myocytes，Cardiovasc. Res.，54: 590-600，2002.

5) Kurata Y, Hisatome I, Imanishi S, Shibamoto T：Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell，Am. J. Physiol. Heart Circ. Physiol.，283: H2074-H2101，2002.

4) Ahmmed GU, Hisatome I, Kurata Y, Makita N, Tanaka Y, Tanaka H, Okamura T, Sonoyama K, Furuse Y, Kato M, Yamamoto Y, Ogura K, Shimoyama M, Miake J, Sasaki N, Ogino K, Igawa O, Yoshida A, Shigemasa C.：Analysis of moricizine block of sodium current in isolated guinea-pig atrial myocytes : atrio-ventricular difference of moricizine block，Vascul. Pharmacol.，38: 131-141，2002.

3) Yatsuhashi T, Hisatome I, Kurata Y, Sasaki N, Ogura K, Kato M, Kinugasa R, Matsubara K, Yamawaki M, Yamamoto Y, Tanaka Y, Ogino K, Igawa O, Makita N, Shigemasa C.：L-cysteine prevents oxidation-induced block of the cardiac Na⁺ channel via interaction with heart-specific cysteinyl residues in the P-loop region，Circ J.，66: 846-850，2002

2) Hongo M, Hironaka E, Yokoseki O, Watanabe N, Shibamoto T, Owa M, Ryoke T：Effects of growth hormone following chronic angiotensin-converting enzyme inhibition in chronic heart failure: their relation to infarct size，Cardiovasc Drugs Ther，15: 241-249，2001.

1) Ogura T, Imanishi S, Shibamoto T：Activation of background membrane conductance by the tyrosine kinase inhibitor tyrphostin A23 and its inactive analog tyrphostin A1 in guinea-pig ventricular myocytes，Jpn. J. Pharmacol.，87: 235-239，2001.